![The Substance [Portuguese]](https://pbcdnw.aoneroom.com/image/2026/01/26/ecb623a49694d5828a0bc49f683422b9.jpg)
A fading celebrity takes a black-market drug: a cell-replicating substance that helps her create a younger, better version of herself.
Trailer
Cast
Demi Moore
Elisabeth
Margaret Qualley
Sue
Dennis Quaid
Harvey
EH
Edward Hamilton-Clark
Fred
Gore Abrams
Oliver
Oscar Lesage
Troy
Christian Erickson
Man at Diner
Robin Greer
Male Nurse
Tom Morton
Doctor
Hugo Diego Garcia
Diego - Boyfriend
Daniel Knight
Casting Director
Jonathon Carley
Assistant Casting Director
Jiselle Henderkott
Girl Auditioning
Jiselle Henderkott
Dancer - New Year's Eve Show
Akil Wingate
TV Host
Billy Bentley
Man in Suit #1 - Harvey's Office
Vincent Colombe
Man in Suit #2
Lennard Ridsdale
Man in Suit #3
Jordan Ford Silver
Assistant Director - Pump It Up Show
Maaari Mo Ring Magustuhan
Katatakutan5.4
Year 10
Katatakutan3.1
Don't Speak
Drama3.6
Rob1n
Drama2.7
Alienate
Krimen8.1
Adolescence
Drama6.8
Fear the Walking Dead
Drama7.9
American Horror Story
Drama6.7
Cassandra
Drama7.2
Glitch
Drama7.2
Glitch
Katatakutan6.7
The Institute
Drama7.4
A Woman of Substance
Komedya5.7
Sistas
Krimen6.7
All the Queen's Men
Krimen4.5
The Oval
Drama5.9
Beauty in Black
Krimen8.0
Lucifer
Aksyon7.2
Avatar: The Last Airbender
Drama8.6
Stranger Things
Aksyon8.5
Vikings
Drama8.3
The Originals
Aksyon8.5
The Boys
Krimen4.8
Ruthless
Komedya7.7
My Demon
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Beautiful henryMar 5, 2026
Gigi PNFeb 8, 2026